Welcome toGeniouskin

The Intelligent Skin Revolution

About Us

Geniouskin creates a living skin substitute using the patient’s own cells.

Geniouskin

Geniouskin is an advanced autologous skin regeneration platform designed to rebuild living, functional, and naturally pigmented skin.

By combining the three essential skin cell types, keratinocytes, fibroblasts, and melanocytes — into a single therapeutic construct, Geniouskin aims to go beyond simple wound coverage and restore the structure, biology, and appearance of real human skin.

Watch the video learn more

Technology

Two steps. One cure.

The Process

Geniouskin’s Process AI continuously monitors cell culture conditions in real time —analyzing growth patterns, detecting contamination risks, and determining the optimal timing for each production stage — reducing variability and cutting manufacturing costs by an estimated 25–40% at scale.

AI Clinical

Geniouskin’s Clinical AI analyzes wound photography at each follow-up visit to track re-epithelialization progress, predict healing trajectory, and flag early signs of complication —giving clinicians a standardized, data-driven decision support tool that strengthens evidence

generation across every treated patient

Roadmap

From bench to bedside

A clear path forward from research to market launch.

2027

Phase 0 complete

Q1–Q2 2027: Patients 2–5 treated sequentially Phase 0 cannot be rushed — we need the safety data before advancing.


Q3–Q4 2027: Phase 0 completion report. 2028 — Phase I running

2028

Phase I completion

Q1 2028: Phase I first 6–12 patients


Q4 2028: Phase I completion.

2029–2030

Phase II multi-site EU 50–150 patients.

2031 — EMA submission


2033 — Commercial launch

Our Team

A highly qualified team combining clinical, scientific, and business expertise.

Prof. Vincent Casoli
President & Inventor

Professor Vincent Casoli, MD, PhD is a leading plastic and reconstructive surgeon and Professor at the University of Bordeaux, where he also headed the Plastic & Reconstructive Surgery Department at the CHU de Bordeaux.

Renowned for his expertise in complex reconstruction, burns, and microsurgery, he operates at the forefront of clinical innovation. He is the co-inventor of Geniouskin®️, a breakthrough autologous engineered skin designed to restore both function and pigmentation, bridging cutting-edge regenerative medicine with real-world surgical application. 

Combining surgical excellence with translational research, Professor Casoli is a key figure shaping the future of advanced skin reconstruction and regenerative therapies.

Patrick Alexandre
CEO

Patrick Alexandre is a serial entrepreneur and strategic builder with cross-sector experience across the United States and Europe.

He brings to Geniouskin a proven track record in brand positioning, business development, and stakeholder orchestration, having structured and scaled ventures across multiple industries before redirecting his expertise toward deep tech and life sciences.

At Geniouskin, Patrick leads the company’s strategic development: from structuring the clinical development pathway, to building the investor narrative, managing regulatory strategy partnerships, and positioning Geniouskin as a next-generation leader in regenerative medicine.

His role bridges the scientific and industrial ambitions of the project — translating a breakthrough technology into a credible, fundable, and scalable clinical platform.

Dr. Muriel Cario (Cario-André)
Inventor
Dr. Muriel Cario (Cario-André) is a senior research scientist at INSERM and a leading expert in skin biology, specializing in pigmentation disorders and tissue-engineered skin. Based at the University of Bordeaux, she has made significant contributions to understanding conditions like vitiligo and melasma, and pioneered advanced 3D skin models.

She is also co-inventor of Geniouskin, the first pigmented artificial skin designed for clinical use, bridging cutting-edge research with real-world dermatological applications.

Jean Christophe le pivert
Inventor

Plastic Reconstructive and Aesthetic Surgery,

Bordeaux University Hospital, France

Expert in acute and chronic wounds,

Director of Burn unit

Participation for GENIOUSKIN technology development

The proof

Pre-clinical validation complete.

Preclinical, murine model.

40M

patients worldwide with chronic wounds

$25B

annual global wound care market

70%

recurrence rate with current treatments

100%

graft take rate in pre-clinical models